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DNase I (RNase-free )

Product Details

Deoxyribonuclease I (DNase I) is an endonuclease that degrades doubleand single-strand DNA and chromatin. It functions by hydrolyzing phosphodiester linkages, producing mono and oligonucleotides with a 5'-phosphate and a 3'-hydroxyl group. Ribonuclease has been reduced to non-detectable levels. Its activity depends on Mg2+ or Mn2+ ion. DNase I with Mg2+ cuts randomly double strand DNA at any site, DNase I with Mn2+ cuts double strand DNA at the same site to form sticky-end with 1-2 nucleotide or form blunt-end.

Concentration: 3 units/μl

At -20˚C for two years.

Dry ice (-70℃).

Product Contents

DNase I (3 units/μl)1500 units
10×DNase I Reaction Buffer2×1 ml
200 mM EDTA1 ml


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