CD105, also known as Endoglin, is a type I transmembrane protein located on the cell surface, consisting of homodimers with a molecular weight of about 90 kD. CD105, one of the TGF-β receptor complexes, highly binds TGF-β1 and β3, but does not bind to β2. CD105 is highly expressed in vascular endothelial cells and is a molecular marker of tumor angiogenesis. In addition, CD105 is also expressed on the surface of activated monocytes and macrophages. After purification of CD105 monoclonal antibody by affinity chromatography, the antibodies were conjugated with fluorescein APC under optimal conditions and used for flow cytometric detection of CD105 on cell surface.
Product Information
Specificity: Human
Host Species: Mouse
Antibody Type: Monoclonal
Clone Number: Trans-7B2
Antibody Subtype: Mouse IgG1, κ
Label: APC (Ex: 633-647 nm；Em: 660 nm)
Stock Solution: Phosphate buffered saline (pH 7.2) containing 1% BSA and 0.05% ProClin 300
Storage
at 2-8°C in dark for one year, do not freeze
Shipping
Ice bag
Bio-Medicine
In Vitro Diagnostics
PCR, RT-PCR, qPCR, qRT-PCR
Restriction/Modifying Enzymes
DNA Molecular Weight Standards
Cloning and Mutagenesis System
Nucleic Acid Purification
Next Generation Sequencing
Gene Expression
Protein Analysis
Protein MW Standards
Cell Culture and Detection
Exosome Related
Serum-free medium
Antibodies
ELISA
Instruments
Residual DNA Detection
