CD8, also known as T8 or Leu2, is a type I transmembrane glycoprotein. It is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells and NK cells. As a co-receptor of MHC class I restricted T cell receptor, CD8 plays an important role in antigen recognition, signal transduction, T cell activation and thymus differentiation. CD8 usually exists as a dimer formed by α and β chains (CD8αβ) or two α chains (CD8αα). Among them, the CD8α chain is also called CD8a, and the CD8β chain is also called CD8b. Trans-8B9 monoclonal antibody specifically recognizes the CD8a molecule. After purification of Trans-8B9 monoclonal antibody by affinity chromatography, the antibodies were conjugated with fluorescein PE under optimal conditions and used for flow cytometric detection of CD8a on cell surface.
Storage
at 2-8°C for one year
Shipping
ice bag (4℃)
Bio-Medicine
In Vitro Diagnostics
PCR, RT-PCR, qPCR, qRT-PCR
Restriction/Modifying Enzymes
DNA Molecular Weight Standards
Cloning and Mutagenesis System
Nucleic Acid Purification
Next Generation Sequencing
Gene Expression
Protein Analysis
Protein MW Standards
Cell Culture and Detection
Exosome Related
Serum-free medium
Antibodies
ELISA
Instruments
Residual DNA Detection
