CD73 is a 70 kD homodimer consisting of 2 identical subunits anchored externally to the cell surface by a glycosyl phosphatidyl inositol (GPI). It can hydrolyze Adenosine monophosphate (AMP) into adenosine. CD73 is expressed in T lymphocytes, B lympho- cytes, mesenchymal stem cells, foaming tree dendritic cells, endothelial cells, and epithelial cell sub-groups, which costimulate the activation of T cells and regulates the adhesion of lymphocytes and endothelial cells. CD73, as a marker of lymphocyte differentiation, is attenuated in some immunodeficiency diseases. According to research reports, CD73 is a potential biomarker, which is closely related to the adverse prognosis of various types of tumors. After purification of CD73 monoclonal antibody by affinity chromatography, the antibodies were conjugated with fluorescein APC under optimal conditions and used for flow cytometric detection of CD73 on cell surface.
Product Information
Specificity: Human
Host Species: Mouse
Antibody Type: Monoclonal
Clone Number: Trans-1H4
Antibody Subtype: Mouse IgG1, κ
Label: APC (Ex: 633-647 nm; Em: 660 nm)
Stock Solution: Phosphate buffered saline (pH 7.2) containing 1% BSA and 0.05% ProClin 300
Storage
at 2-8°C in dark for one year, do not freeze
Shipping
Ice bag
Bio-Medicine
In Vitro Diagnostics
PCR, RT-PCR, qPCR, qRT-PCR
Restriction/Modifying Enzymes
DNA Molecular Weight Standards
Cloning and Mutagenesis System
Nucleic Acid Purification
Next Generation Sequencing
Gene Expression
Protein Analysis
Protein MW Standards
Cell Culture and Detection
Exosome Related
Serum-free medium
Antibodies
ELISA
Instruments
Residual DNA Detection
