CD4 is a single-chain type I transmembrane glycoprotein with molecular weight of 55 kD, which is mainly expressed in helper T cells, NKT cells, monocytes, macrophages and dendritic cells etc. CD4 is a co-receptor for T-cell receptor (TCR) to recognize antigens, which binds to the non-polypeptide region of MHC class II molecules, and participates in signal transduction during TCR recognize antigen. CD4 is also the main receptor for HIV. In macrophages or NKT cells, CD4 regulates cell differentiation, activation, cytokine expression and cell migration through TCR/LCK-independent signaling pathway. After purification of CD4 monoclonal antibody by affinity chromatography, the antibodies were conjugated with fluorescein PE under optimal conditions and used for flow cytometric detection of CD4 on cell surface.
Storage
at 2-8°C for one year
Shipping
ice bag (4℃)
Bio-Medicine
In Vitro Diagnostics
PCR, RT-PCR, qPCR, qRT-PCR
Restriction/Modifying Enzymes
DNA Molecular Weight Standards
Cloning and Mutagenesis System
Nucleic Acid Purification
Next Generation Sequencing
Gene Expression
Protein Analysis
Protein MW Standards
Cell Culture and Detection
Exosome Related
Serum-free medium
Antibodies
ELISA
Instruments
Residual DNA Detection
